However, researchers have found a “nocebo” effect when it comes to perceived muscle pain and statins. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult. You may feel this pain as a soreness, tiredness or weakness in your muscles. One of the most common complaints of people taking statins is muscle pain. What are statin side effects? Muscle pain and damage Their average age was 68.5 years at the start of the study. The current study included nearly 500,000 men and about 10,000 women. Veterans Administration (VA) recommended only moderate doses, noting the lack of conclusive evidence that higher-dose statins are more beneficial. The evidence about statins’ benefits for those over 75 is limited due to their small numbers in clinical trials, the researchers noted in the study. For example, in 2013, the American College of Cardiology and the American Heart Association jointly recommended a risk-based strategy and giving high doses of statin therapy for those with cardiovascular disease with narrowed arteries for all who were under age 75 if they could tolerate it. Major guideline-issuing organizations haven’t come up with consistent recommendations for statin dosing, study authors said. The bottom line, Rodriguez said, is that “if you have had a cardiovascular event, you should be on high-intensity statin therapy and you should be on the highest dose you are able to tolerate.” She’s a cardiovascular medicine fellow at Stanford University School of Medicine in Palo Alto, Calif. The study showed that people over 75 also have a survival benefit with high doses compared to moderate doses, said study author Dr. Unlike some previous studies, this study included adults over age 75. Examples of moderate doses include 10 to 20 mg of Lipitor and 5 to 10 mg of Crestor, the study reported. High doses - also called high-intensity statin therapy - included 40 to 80 milligrams (mg) of atorvastatin (Lipitor) or 20 to 40 mg of rosuvastatin (Crestor) daily. The researchers found that survival increased by 9 percent when people took high versus moderate doses of statin for a little over a year. The study followed more than 509,000 patients with various forms of cardiovascular disease. Higher doses of the cholesterol-lowering drugs known as statins appear to boost survival slightly for certain people, a large new study reports. Just take your next dose as usual the following day. If you forget to take your dose, do not take an extra one to make up for it. You usually have to continue taking statins for life because if you stop taking them, your cholesterol will return to a high level within a few weeks. Check with your doctor whether there’s a particular time of day you should take your statin. Some types of statin like Atorvastatin should be taken in the evening. For some types of statin it does not matter what time of day you take it, as long as you stick to the same time. Statins come as tablets that are taken once a day. your personal and family medical history suggests you’re likely to develop CVD at some point over the next 10 years and lifestyle measures have not reduced this risk.you have been diagnosed with a form of CVD.stroke – when the supply of blood to the brain becomes blockedĪ doctor may recommend taking statins if either:.
heart attacks – when the supply of blood to the heart is suddenly blocked.angina – chest pain caused by reduced blood flow to the heart muscles.
0 kommentar(er)
